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IVF (In Vitro Fertilization)

Overview

IVF (In vitro fertilization)

Achieving parenthood is the greatest blessing and one of the most joyous experiences of life.
Around 15% of the couples would find it difficult to get pregnant naturally. We at Dr L H Hiranandani Hospital, Powai, provides you the best IVF treatment in Mumbai at our Centre for Human Reproduction. Being one of the best IVF hospitals in Mumbai, we guide you through this bumpy journey with few interventions and make the process smooth and hassle free.

 

Why IVF Treatment Require

According to studies, people visiting an IVF center in Mumbai are suffering through certain types of lifestyle disorders such Diabetes, obesity, strokes, and others. Unhealthy habits such as smoking, stress, junk food, and others can also increase infertility issues. Quick urbanization, hormonal growth, work pressure, vehicular pollution, and postponing parenthood are some lesser-known reasons for infertility in India. To handle such cases, we follow an individualized approach, understanding the root cause of infertility and treating it appropriately with tailor made investigations and procedures.

 

IVF clinic in Mumbai

In our fertility clinic, we offer all types of investigation and treatment under one roof. Our hospital has the most affordable IVF clinic in Mumbai with all advanced equipment and highly skilled doctors. Besides the treatment, a balanced lifestyle and stress management also plays an important part. At our best IVF clinic, we also stress on lifestyle and stress management before any further advanced treatments.

 

In some cases, medical treatments are performed to improve egg and sperm quality. Removing polyps, fibroids, benign tumors are also helpful for fast pregnancy without further intervention.

For further procedure, our fertility center provides various treatment from IUI to IVF/ICSI (Intra Cytoplasmic Sperm Injection), advanced treatment such as PICSI, Laser assisted hatching, blastocyst transfer, PRP and GCSF treatment also the thin lining to donor egg program and surrogacy, all under one roof.

 

Best IVF Hospital In Mumbai

Our centre at the Dr L H Hiranandani Hospital is one of the best IVF hospitals in Mumbai, we believe in taking a holistic approach with a personal touch for the treatment of infertility problems. We are committed to provide you, with the most advanced medical treatment available, offered in an empathetic and caring environment. Our team includes highly- trained doctors, embryologists and nurses, all experts in their areas of specialization. We provide best quality, individualized, compassionate fertility care at our IVF clinic, providing the best IVF treatment in Powai.

 

Achieving parenthood is the greatest blessing and one of the most joyous experiences of life.
Around 15% of couples would find it difficult to get pregnant naturally. We at Dr L H Hiranandani Hospital, Powai, provides you the best IVF treatment in Powai at our Centre for Human Reproduction. Being one of the best IVF hospitals in Mumbai, we guide you through this bumpy journey with few interventions and make the process smooth and hassle-free.

 

IVF Center / Department in Mumbai

Our IVF Department is located on the 3rd floor of the Hospital. It is a spacious and secluded department spread over an area of over 2500 sq. ft.
The department has a separate OPD waiting area with USG and IUI rooms and a modern operation theatre with state of art Andrology and ICSI laboratories. The operation theatre and laboratories are equipped with the best and most modern equipments fulfilling all the requirements of a Centre par excellence comparable to any other in the world.
The main advantage of our Centre is that all the facilities from investigations to all modalities of treatment are available under one roof.
It is the dream of most men and women to become parents and have children to love and care for. It is one of the greatest blessings in a lifetime to become a parent.

 

 

Why Choose DR L H Hiranandani Hospital for IVF Treatment in Mumbai

We at our center have a different approach to a couple with sub fertility. It is an individualized approach, understanding the root cause of infertility and treating it appropriately with tailor made investigations and procedures. We have an in depth counseling and discussion session with you about the probable cause of your sub fertility and different treatment options available for you. We discuss different pros and cons for each treatment option and help you in selecting the correct option.

 

 

 

Facilities Available at Our IVF clinic in Mumbai

We help you – by providing these facilities under one roof.

 

  • Blood tests (hormonal profile)
  • X- ray (HSG) for tubal assessment.
  • Ultrasound (TVS).
  • Sonohystero salpingography
  • Doppler (Sub endometrial blood flow).
  • Endoscopy (laparoscopy / hysteroscopy).
  • Semen Analysis.
  • Ovulation induction.
  • Intra uterine insemination; AIH, Donor IUI.
  • InVitro Fertilization (IVF).
  • Intra Cytoplasmic Sperm Injection (ICSI).
  • Testicular Aspiration & Biopsy (PESA, TESA, TESE).
  • Embryo Cryopreservation/ Egg Cryopreservation for future pregnancy.
  • Preimplantation Genetic Screening(PGS)/ Preimplantation Genetic Diagnosis(PGD)
  • Donor Oocyte program
  • Surrogacy.

 

Procedures done in the department

 IUI

Intra-uterine insemination (IUI) is a process in which the washed sperms are placed directly into the uterus with the help of a thin catheter. IUI is an OPD (outpatient department) procedure in which neither anesthesia nor hospitalization is required. Ovulation is confirmed by ultrasound and once it is done, the partner is asked to collect the semen in a sterile container. It takes about 45 minutes to an hour to process the semen sample. A thin tube called IUI catheter is introduced in the uterus & the processed semen sample is slowly released in the uterus. Luteal phase support is given and pregnancy is confirmed fifteen days later by a simple blood test. This is well performed in our fertility clinic.

 IVF/ICSI (Intra Cytoplasmic Sperm Injection)

IVF stands for in vitro fertilization. It refers to the process in which a woman’s eggs are collected and later fertilized outside her womb in the laboratory. We are presently the bestIVF center in Mumbai for services such as infertility, sperm donation and others. ICSI (Intra Cytoplasmic Sperm Injection) has proved to be very useful in couples who have failed to achieve fertilization or had very poor fertilization following standard IVF treatment & in couples where the male partner has abnormal sperm parameters (e.g. low count, poor motility, high percentage of abnormal sperms).

In our fertility clinic the IVF / ICSI ((Intra Cytoplasmic Sperm Injection) procedures do not require overnight hospitalization.

 DONOR EGG PROGRAM

Our infertility doctors of our IVF clinic in Mumbai have started the Donor Egg Program. In this program another woman will be the egg donor. The donor is chosen after a strict medical evaluation and after relevant investigation. After getting normal results, the donor will undergo IVF stimulation under our top infertility experts in Mumbai and later followed by ovum Pick up. The donor’s eggs are fertilized with the recipient’s husband’s sperms. The resultant embryos are then transferred in the adequately prepared uterus of the recipient.

 SURROGACY

In women where have conditions of her uterus is malformed or damaged and is incapable of carrying a pregnancy due repeated miscarriages or women suffering from medical problems whom a pregnancy would be life threatening or women who have had a surgical removal of the uterus due to cancer, ruptured womb or who are born without a uterus, these are some of the conditions where surrogacy is indicated in these women.
The term Surrogacy is used when a woman carries a pregnancy and gives birth to a baby for another woman .Surrogate carries the pregnancy and is genetically not related to the child. Our IVF clinic helps the patient through this entire journey in consultation with the best IVF doctors.

 

 

FERTILITY ENHANCING SURGERIES

Fertility enhancing surgeries like Laparoscopy & Hysteroscopy when done indicated improve the pregnancy rate, sometimes without intervention

 

At the best IVF center in Mumbai, we perform the following Latest Techniques to Improve the Pregnancy Rate

 

Blastocyst transfer

A blastocyst is the final stage of the embryo’s development before it hatches out of the
shell (zona pellucida) and implants in the uterine wall.  Our fertility clinic in Powai     transfers the embryo on day 5, at the blastocyst stage, yields higher pregnancy rate.

 

 

Laser Assisted Hatching

Assisted hatching is performed in the laboratory just prior to embryo transfer under supervision of our infertility doctors. Assisted hatching is performed in the laboratory just prior to embryo transfer. It is a simple and precautionary procedure where a small hole is made in the outside shell (the zona) of each embryo to be transferred.

 

Subendometrial Blood Flow

Low implantation rates in stimulated IVF cycles may be related to suboptimal
endometrial perfusion. This can be easily diagnosed by a non-invasive test like sonography with Doppler ultrasound performed at out fertility clinic in Powai.
This poor blood flow can be then be improved by alteration in medications and the pregnancy rate can be improved. This is done by direct supervision of infertility doctors who are experts.

 

 

PICSI (PHYSIOLOGICAL ICSI)

PICSI sperm selection device is now available for the selection of mature sperm for ICSI (Intra Cytoplasmic Sperm Injection). These selected sperms will have minimal DNA fragmentation, normal shape and low frequency of chromosomal aneuploidies improving pregnancy rate and also reducing the rate of abortions. All this is identified with great skill in the fertility clinic and also under supervision of the best team of fertility doctors.

 

 

GROWTH HORMONE

 

Growth Hormone therapy is one of the adjuvant treatment used in ovarian stimulation and ART. Growth Hormone supplements have shown to improve pregnancy rates in poor responders. This is done in IVF hospitals but arguably by the best IVF doctors in our fertility clinic.

 

GCSF ( Granulocyte colony stimulating factor)

 

G-CSF is a cytokine/growth factor crucial for implantation and it is also a remedy for implantation failure, recurrent abortions, and thin endometrium which fails to respond with standard therapy. This is a process that has been well practiced by our best IVF clinic.

 

Platelet Rich Plasma (PRP)

Endometrium is one of the main factors in implantation and pregnancy. Pregnancy rate is increased with growing endometrial thickness
Intrauterine infusion of platelet-rich plasma (PRP) is a new approach that has been suggested for the treatment of thin endometrium by the best hospitals for infertility practise.

 

 

preimplantation genetic screening (PGS)

For testing whether embryos (obtained through IVF/ICSI) have abnormal chromosomes number is also offered as a service in our fertility centre.

 

 

Pre-implantation genetic diagnosis (PGD)

 

It is the testing of pre-implantation stage embryos or oocytes for genetic defects. It has been developed for couples whose potential offspring are at risk of severe Mendelian disorders, structural chromosome abnormalities or mitochondrial disorders. This is a service offered by arguably the best hospital for infertility.

 

Achievement of our IVF treatment in Mumbai :

A 42 yr old patient with thin endometrium (less than 7 mm)  and poor ovarian reserve who already had   one  failed cycle of  IVF came to us for further treatment .
The treatment given :
Medicines to improve the egg quality were given for 12 weeks before the IVF procedure.
IVF was done and embryos were frozen.
Hysteroscopic Metro plasty was done to correct the endometrial cavity .In the next cycle
estradiol valerate tablets were started for embryo transfer. Inspite  of successive increase in the dose of estradiol valerate,  when her lining did not grow beyond 7.5  mm Platelet Rich Plasma (PRP) was inserted  in the uterine cavity .
The embryo transfer was done 3 days after the PRP and patient had a healthy pregnancy and delivery.

 

Facilities/ Services

Facilities available

  • Ovulation Induction
  • Fertility Enhancing Laparoscopic Surgeries
  • Investigations

Basic investigations required and done are:

  1. Serum TSH
  2. Serum Prolactin
  3. FSH or Follicle Stimulating Hormone
  4. LH or Luteinizing Hormones
  5. FSH/LH ratio
  6. Endometrial blood flow
  7. Hysterosalpingogram (HSG)
  8. AMH or Antimullerian hormone – Ovarian Reserve Analysis

 

Services available

Counseling and lifestyle management
Today’s lifestyle incorporates a lot of stress, irregular working hours, irregular sleep patterns, eating habits, Increasing age of marriage, career aspirations, postponing childbearing, nuclear families smoking, alcohol etc. have taken a toll on fertility.

Therapy of many of the causes of infertility includes lifestyle management comprising of diet and includes a little different thinking, in-depth knowledge of different causes of infertility, use of various modalities the foremost being lifestyle modification. The treatment for your infertility maybe just lifestyle modification. Why subject a patient to IVF/ICSI when only lifestyle modification and ovulation induction may do the trick?

 

IUI

Q. What is IUI?

  • Minimally invasive fertility enhancing procedure
  • OPD procedure
  • Not painful
  • No fasting required
  • No bed rest after IUI
  • Can go to work in the second half of the day after the procedure
  • Improves pregnancy outcome significantly

Indications of IUI

  1. Low sperm count and motility (male factor infertility)
  2. Unexplained infertility –along with ovulation induction
  3. Endometriosis
  4. PCOS
  5. Sexual dysfunction
  6. Absence of male partner at the time of ovulation (using frozen sperms)

 

IVF (In Vitro Fertilization) / ICSI

What is IVF/ICSI?

  • One of the cost effective procedures
  • Not as complicated as it seems
  • 8-10 visits required to the clinic
  • Injections are subcutaneous injections (like insulin injections), can be taken on your own.
  • Injections are not painful
  • No need to take leave for the entire period of the procedure
  • No bed rest required post transfer. Can resume work 3-4 days post transfer.
  • No oil based injections post transfer (Most patients are scared of this and hence some postpone IVF)
  • Day care procedure (Both oocyte retrieval and embryo transfer) – Can go home by afternoon. No overnight hospitalization
  • Oocyte retrieval requires short intravenous anesthesia
  • No cuts/incisions on the abdomen
  • Embryo transfer is as simple as IUI (No fasting/anesthesia required)

 

Donor egg programme

  • Donor Egg programme is one of the programme’s with highest success rate.
  • Proper pre IVF evaluation and co-ordination with donor and fresh embryo transfer gives the best results.

 

Surrogacy

Why surrogacy at Dr L H Hiranandani Hospital?
At Dr L H Hiranandani Hospital, we have

  • High volume of patients – Arguably we deliver the largest number of surrogates for a single hospital in Mumbai
  • Facilitation of the birth certificate – The process of obtaining birth certificate is systematically placed so that the application and processing is done in the shortest possible time.
  • NABH accredited & ISO certified Hospital - All rules and protocols are in place and they are strictly followed according to standard operating procedures. This gives standardization to all the procedures we do and helps in maintaining strict quality control.

Facilities available for Surrogacy

All facilities under one roof – Investigations, ICSI cycle etc. and all the procedures for the surrogate antenatal check ups as well as delivery, neonatal care post delivery pediatric care and advice are conducted in the Hospital.

  • The NICU is well equipped to handle very small, preterm babies and all the complications associated with prematurity
  • A fully equipped hi tech OT setup comparable to international standards available day and night to handle emergencies.
  • 24 hrs radiology department/USG facilities
  • 24 hrs NABH Accredited blood bank and casualty services
  • 24 hours NABL Accredited pathology laboratory
  • Webcam facility available - We are available to talk to you at predetermined date and time so that we can have a direct discussion as if you are doing a consultation with us. You can clarify all your doubts personally rather than on mail.
  • High success rate with practically nil preterm deliveries - This is because of the meticulous care in choosing the surrogate as well as care taken during pregnancy. She is treated as a high risk pregnancy with two obstetricians taking care of her.
  • Novel ways like cervical length monitoring by transvaginal sonography & antibiotic and probiotic treatment during pregnancy to prevent preterm labor- These new ways of monitoring have practically eradicated preterm delivery, the most dreaded complication of pregnancy. We have presented papers on these novel methods in various Conferences and they have received due recognition.
  • Optimization of pregnancy outcome - At our centre, we believe that the success rate of IVF/ICSI depends on pre IVF evaluation. E.g. If there is poor ovarian reserve, then we give certain medications before IVF to improve the ovarian reserve and then attempt IVF. This obviously gives a high success rate. Similarly all male and female factors are evaluated before going for the actual cycle.
    Thus high IVF success rates with high surrogacy rates gives us the best results
  • Extended embryo culture / Blastocyst transfer - The quality of any laboratory is assessed by the number of blastocyst transfers. Our IVF laboratory is fully equipped with all the modern, state of art technology and expertise which gives us a high fertilization rate and we do blastocyst transfer in at least 70% of the patients.
  • Blood flow monitoring - It is a novel concept in the science of infertility. It is like seed and soil. When you sow the seed under the soil and give water, that water has to percolate the soil and reach the seed; otherwise the seed will not develop into a plant. Similarly if the blood flow does not reach the inner lining of the uterus, the embryo will not get nutrition and will not implant or if it implants may lead to missed abortion. Endometrial perfusion presents accurate noninvasive assay of uterine receptivity that may be used to predict implantation success rate. We select only those surrogates who have good blood flow thus increasing the success rates.

Services

  • Well known three full time obstetricians with vast experience available in case of any emergency.
  • Three full time Pediatrician & neonatologists attending to the newborn's every need. They are present at the time of all deliveries and Caesareans.
  • A team of 6 highly qualified full time anesthetists handle the operation theater (OT), one of them being on the campus at any given time. So in case of emergencies there is no delay in taking patient to the OT.
  • In case there is a need to transfer the patient to ICU, world class well equipped setup with full time intensivist is available.
  • Advice on Breastfeeding - Breast feeding is an integral part of child birth and helps to create a bond between mother and baby.
  • All transactions by wire transfer - All your payments can be easily done through your bank by wire transfer
  • Collateral legal support
  • Our lawyer will not only help you with all the paperwork for surrogacy but will also guide you correctly about the paperwork required to obtain a fast visa for the child.
  • Ethic committee approval of surrogate - The surrogate is presented in front of the ethic committee which comprises of people from various walks of life including priests, businessmen, social activists etc. They assess the surrogate psychologically by asking various questions. This is recorded on camera. This also gives a solid legal backing should the need arise.
  • Timely and detailed update to commissioning couple including USG videos - All the reports and details of the surrogate are provided to the commissioning couple as soon as we get the reports
  • Detailed evaluation of surrogate before registering her for the program - This is done to ensure maximum success rates. A dummy cycle with endometrial blood flow monitoring is done before the actual cycle.
  • Personal & human touch - The compassion, the personal touch, and the care that we offer for both the surrogate and the biological mother makes our program a little different and unique.

Our Team

Full Time Consultant
Name Designation Qualification Availability
Dr. Hetal Parekh Full Time Consultant IVF M.D.( Obs. & Gynaec), DNB (Obs. & Gynaec)
  • 8.00 am – 8.00 pm
Dr. Vrushni Bhuta Consultant Reproductive Medicine M.B.B.S.,MS (Obstetrics and Gynecology), Fellowship in Endoscopy

Visiting Consultant
Name Designation Qualification Availability
Dr. Yashodhara Mhatre Honorary Consultant IVF MD (Obstetrics & Gynaecology), DGO, Fellow – IVF (Singapore)

Monday to Saturday : 11.00 am - 8.00 pm